Current events
From LMP Journal Club
Date: Jun 17th
Time: 09:30 am
Place : 2nd Floor Conference Room, Gonda building.
Title : "Insulin Signaling and Dietary Restriction Differentially Influence the Decline of Learning and Memory with Age"
Speaker: Kelsey Martin
Summary: This paper from Coleen Murphy's lab at Princeton describes a novel assay for short and long-term associative memory in the worm c. elegans. Using this assay, the authors show that long-term memory declines very early in c elegans, before any deficits in chemotaxis or motility. Analysis of genetic mutants identifies a specific role for CREB during long-term memory, and further reveals that long-term memory is differentially regulated by the insulin/IGF-1 and dietary restriction longevity pathways.
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