Difference between revisions of "ICLM Journal Club"
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''' History of ICLM ''' | ''' History of ICLM ''' | ||
| − | The Integrative Center for Learning and Memory formally LMP started in its current form in 1998, and has served as a platform for many interactions and collaborations within UCLA. A key event organized by the group is the weekly ICLM Journal Club. For more than 10 years, graduate students, postdocs, principal investigators, and invited speakers have presented on | + | The Integrative Center for Learning and Memory formally LMP started in its current form in 1998, and has served as a platform for many interactions and collaborations within UCLA. A key event organized by the group is the weekly ICLM Journal Club. For more than 10 years, graduate students, postdocs, principal investigators, and invited speakers have presented on topics ranging from the molecular mechanisms of synaptic plasticity, through computational models of learning, to behavior and cognition. Dean Buonomano oversees the ICLM journal club with help of student/post doctoral organizers. For other events organized by ICLM go to http://www.iclm.ucla.edu/Events.html. |
| − | Current | + | Current Organizers: |
Walt Babiec (O'Dell Lab) | Walt Babiec (O'Dell Lab) | ||
| − | Past | + | Past Organizers: |
| − | i) Anna | + | i) [http://www.linkedin.com/pub/anna-matynia/5/55b/99 Anna Matynia](Aug 2004 - Jun 2008) ([http://www.silvalab.org Silva Lab]) |
ii) Robert Brown (Aug 2008 - Jun 2009) ([http://faculty.psych.ucla.edu/directory/faculty.php?id=67&area=5 Balleine Lab]) | ii) Robert Brown (Aug 2008 - Jun 2009) ([http://faculty.psych.ucla.edu/directory/faculty.php?id=67&area=5 Balleine Lab]) | ||
| − | iii) Balaji Jayaprakash (Aug 2008 - Nov 2011) ([http://www.silvalab.org Silva Lab]) | + | iii) [http://www.cns.iisc.ernet.in/balaji/index.html Balaji Jayaprakash] (Aug 2008 - Nov 2011) ([http://www.silvalab.org Silva Lab]) |
| − | iv) Justin Shobe & Thomas Rogerson (Dec 2011 - June 2013) ([http://www.silvalab.org Silva Lab]) | + | iv) [http://www.silvalab.org/lab_members/current_lab_members.html Justin Shobe] & [http://med.stanford.edu/profiles/postdocs/researcher/Thomas_Rogerson/ Thomas Rogerson] (Dec 2011 - June 2013) ([http://www.silvalab.org Silva Lab]) |
='''Wiki Newbies'''= | ='''Wiki Newbies'''= | ||
Revision as of 01:44, 23 January 2014
This Week
Date: 24 January 2014
Time: 09:30 am
Place : Gonda 2nd Floor Conference Room
Title: A Cholinergic Mechanism for Reward Timing within Primary Visual Cortex
Speaker: Helen Motanis (Buonomano lab)
This week I have chosen a paper entitled ‘A Cholinergic Mechanism for Reward Timing within Primary Visual Cortex’ by Chubykin et al. 2013. Neurons in rodent primary visual cortex (V1) relate operantly conditioned stimulus-reward intervals with modulated patterns of spiking output, but little is known about the locus or mechanism of this plasticity. The authors show that cholinergic basal forebrain projections to V1 are necessary for the neural acquisition, but not the expression, of reward timing in the visual cortex of awake, behaving animals. The authors also mimic reward timing in vitro by pairing white matter stimulation with muscarinic receptor activation at a fixed interval and show that this protocol results in the prolongation of electrically evoked spike train durations out to the conditioned interval. Together, these data suggest that V1 possesses the circuitry and plasticity to support reward time prediction learning and the cholinergic system serves as an important reinforcement signal, which, in vivo, conveys to the cortex the outcome of behavior.
About Us
Introduction
The Integrative Center for Learning and Memory (ICLM) is a multidisciplinary center of UCLA labs devoted to understanding the neural basis of learning and memory and its disorders. This will require a unified approach across different levels of analysis, including;
1. Elucidating the molecular cellular and systems mechanisms that allow neurons and synapses to undergo the long-term changes that ultimately correspond to 'neural memories'.
2. Understanding how functional dynamics and computations emerge from complex circuits of neurons, and how plasticity governs these processes.
3. Describing the neural systems in which different forms of learning and memory take place, and how these systems interact to ultimately generate behavior and cognition.
History of ICLM
The Integrative Center for Learning and Memory formally LMP started in its current form in 1998, and has served as a platform for many interactions and collaborations within UCLA. A key event organized by the group is the weekly ICLM Journal Club. For more than 10 years, graduate students, postdocs, principal investigators, and invited speakers have presented on topics ranging from the molecular mechanisms of synaptic plasticity, through computational models of learning, to behavior and cognition. Dean Buonomano oversees the ICLM journal club with help of student/post doctoral organizers. For other events organized by ICLM go to http://www.iclm.ucla.edu/Events.html.
Current Organizers:
Walt Babiec (O'Dell Lab)
Past Organizers:
i) Anna Matynia(Aug 2004 - Jun 2008) (Silva Lab)
ii) Robert Brown (Aug 2008 - Jun 2009) (Balleine Lab)
iii) Balaji Jayaprakash (Aug 2008 - Nov 2011) (Silva Lab)
iv) Justin Shobe & Thomas Rogerson (Dec 2011 - June 2013) (Silva Lab)
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